Across TCGA cell cohorts, HSP90AB3P protein abundance is significantly associated with the RNA expression of many other genes, with 720 significant associations in total. KIDNEY shows the largest number of these associations.

The most reproducible HSP90AB3P-associated genes across cancer lineages are ATPSCKMT, SUCO, and TMEM53. Each is linked with HSP90AB3P in more than 3 cancer types. Because this analysis shows association rather than direction, both HSP90AB3P-to-partner and partner-to-HSP90AB3P results are reported.

Each partner links to its own Q-omics profile.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (HSP90AB3P→partner) and Y-score (partner→HSP90AB3P) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUAD	ATPSCKMT →	+0.897	+1.277	<.001	<.001	3	4
SKIN	SUCO →	-0.732	-1.163	<.001	.003	3	3
LUNG_SCLC	TMEM53 →	+1.007	+1.156	.003	.009	3	3
LUNG_SCLC	CIR1 →	-0.566	-1.066	<.001	.001	3	3
LUNG_SCLC	SLC6A17 →	+2.374	+1.424	<.001	.002	3	3
OESOPHAGUS	SLC27A4 →	+1.347	+1.562	.001	.002	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 720 associations by consensus.

Exploration

HSP90AB3P survival (RNA) · tumor vs normal (RNA) · all HSP90AB3P data types