HSP90AB2P

RNA expression — cross-omics
Cross-omicsRNA → PROTEIN-MSPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, HSP90AB2P RNA expression is significantly associated with the protein abundance of many other proteins, with 10,389 significant associations in total. GBM shows the largest number of these associations.

The most reproducible HSP90AB2P-associated proteins across cancer lineages are USP39, SYTL2, and THOC2. Each is linked with HSP90AB2P in more than 3 cancer types. Because this analysis shows association rather than direction, both HSP90AB2P-to-partner and partner-to-HSP90AB2P results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (HSP90AB2P→partner) and Y-score (partner→HSP90AB2P) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner proteinX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
GBMUSP39 →+0.353+0.421<.001<.00134
BRCASYTL2 →-0.500-0.998.006<.00134
GBMTHOC2 →+0.331+0.444<.001<.00134
HNSCBOD1L1 →+0.225+0.666<.001<.00134
LSCCRFC1 →+0.298+0.368<.001<.00134
GBMNCOA5 →+0.245+0.323<.001<.00133
Each partner links to its Q-omics profile. Showing the 6 strongest of 10,389 associations by consensus.

Exploration