Across TCGA cell cohorts, HSP90AB2P protein abundance is significantly associated with the RNA expression of many other genes, with 3,184 significant associations in total. PANCREAS shows the largest number of these associations.

The most reproducible HSP90AB2P-associated genes across cancer lineages are TIMP2, ANAPC1, and DPH5. Each is linked with HSP90AB2P in more than 6 cancer types. Because this analysis shows association rather than direction, both HSP90AB2P-to-partner and partner-to-HSP90AB2P results are reported.

Each partner links to its own Q-omics profile.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (HSP90AB2P→partner) and Y-score (partner→HSP90AB2P) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	TIMP2 →	-2.599	-0.988	<.001	<.001	3	7
PANCREAS	ANAPC1 →	+0.638	+1.542	.002	.006	3	7
LARGE_INTESTINE	DPH5 →	+0.835	+2.065	.001	<.001	2	7
OVARY	CHMP4B →	-0.639	-1.636	.004	.004	3	6
OVARY	POLR3G →	+1.364	+1.567	.008	.006	2	7
UPPER_AERODIGESTIVE_TRACT	HSPE1 →	+1.358	+1.771	.009	.005	2	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,184 associations by consensus.

Exploration

HSP90AB2P survival (RNA) · tumor vs normal (RNA) · all HSP90AB2P data types