HSP90AA1

protein abundance — cross-omics
Cross-omicsPROTEIN-MS → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, HSP90AA1 protein abundance is significantly associated with the RNA expression of many other genes, with 12,914 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible HSP90AA1-associated genes across cancer lineages are CINP, ATP5MPL, and CDCA4. Each is linked with HSP90AA1 in more than 8 cancer types. Because this analysis shows association rather than direction, both HSP90AA1-to-partner and partner-to-HSP90AA1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, HSP90AA1 versus CINP in OV, with a Pearson correlation of 0.52.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (HSP90AA1→partner) and Y-score (partner→HSP90AA1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
OVCINP →+0.478+0.265<.001<.00139
LSCCATP5MPL →+0.615+0.266<.001<.00139
LSCCCDCA4 →+0.731+0.325<.001<.00139
LSCCGLRX5 →+0.611+0.307<.001<.00138
LSCCVRK1 →+0.815+0.304<.001<.00138
UCECAHSA1 →+0.875+0.195<.001<.00137
Each partner links to its Q-omics profile. Showing the 6 strongest of 12,914 associations by consensus.

HSP90AA1 vs CINP — OV

Per-sample scatter of HSP90AA1 vs CINP in OV (Pearson r = 0.52).

Explore this scatter interactively →

Exploration