HSFY5P

Across TCGA pan-cancer cohorts, HSFY5P RNA is linked to patient survival in 2 of 34 cancer types, making it the most broadly survival-associated HSFY5P data layer.

The strongest signal is observed in skin cutaneous melanoma (SKCM), where higher HSFY5P RNA is associated with worse overall survival. In most high-consensus cancer types, elevated HSFY5P expression acts as an unfavorable survival marker.

SKCM and OV are the cancer types where HSFY5P RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
SKCM	OS	Tertile	All	0.179	0.877	<.001	126	view →
OV	OS	Tertile	IV	0.022	0.760	<.001	90	view →

Pink = unfavorable, green = favorable. Showing the 2 strongest of 2 lineages.

HSFY5P–SKCM (OS)

Open the SKCM breakdown →