HSFX2

Across TCGA patient cohorts, HSFX2 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,943 significant associations in total. STAD shows the largest number of these associations.

The most reproducible HSFX2-associated GO terms across cancer lineages are Microautophagy, Obsolete regulation of histone methylation, and Regulation of autophagy of mitochondrion in response to mitochondrial depolarization. Each is linked with HSFX2 in more than 10 cancer types. Because this analysis shows association rather than direction, both HSFX2-to-partner and partner-to-HSFX2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Microautophagy grouped by HSFX2-low versus HSFX2-high in STAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (HSFX2→partner) and Y-score (partner→HSFX2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	Microautophagy →	+0.026	+0.061	<.001	<.001	3	9
ESCA	Obsolete regulation of histone methylation →	+0.058	+0.120	.002	<.001	1	11
STAD	Regulation of autophagy of mitochondrion in response to mitochondrial depolarization →	+0.037	+0.098	<.001	<.001	3	9
STAD	Obsolete regulation of dosage compensation by inactivation of X chromosome →	+0.037	+0.059	<.001	<.001	3	9
STAD	Positive regulation of mitophagy in response to mitochondrial depolarization →	+0.032	+0.063	<.001	<.001	3	8
STAD	Response to mitochondrial depolarisation →	+0.035	+0.061	<.001	<.001	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,943 associations by consensus.

Microautophagy by HSFX2 expression — STAD

Explore this box plot interactively →