HSFX1

Across TCGA cell cohorts, HSFX1 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,654 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible HSFX1-associated GO terms across cancer lineages are Vesicle-mediated transport to the plasma membrane, Process utilizing autophagic mechanism, and Autophagy. Each is linked with HSFX1 in more than 15 cancer types. Because this analysis shows association rather than direction, both HSFX1-to-partner and partner-to-HSFX1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Vesicle-mediated transport to the plasma membrane grouped by HSFX1-low versus HSFX1-high in UPPER_AERODIGESTIVE_TRACT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (HSFX1→partner) and Y-score (partner→HSFX1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UPPER_AERODIGESTIVE_TRACT	Vesicle-mediated transport to the plasma membrane →	+0.088	+0.521	<.001	<.001	3	16
STOMACH	Process utilizing autophagic mechanism →	+0.086	+0.531	<.001	.001	3	16
STOMACH	Autophagy →	+0.086	+0.531	<.001	.001	3	16
OESOPHAGUS	Regulation of myoblast fusion →	+0.146	+0.442	<.001	.007	3	16
STOMACH	Macroautophagy →	+0.076	+0.408	<.001	.004	3	15
OESOPHAGUS	Negative regulation of organelle assembly →	+0.083	+0.495	<.001	.001	3	15

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,654 associations by consensus.

Vesicle-mediated transport to the plasma membrane by HSFX1 expression — UPPER_AERODIGESTIVE_TRACT

Explore this box plot interactively →