HSF5

Across TCGA patient cohorts, HSF5 RNA expression is significantly associated with the protein abundance of many other proteins, with 9,855 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible HSF5-associated proteins across cancer lineages are LCP2, LCP1, and NFATC2. Each is linked with HSF5 in more than 6 cancer types. Because this analysis shows association rather than direction, both HSF5-to-partner and partner-to-HSF5 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, HSF5 versus LCP2 in UCEC, with a Pearson correlation of 0.31.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (HSF5→partner) and Y-score (partner→HSF5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	LCP2 →	+0.470	+0.409	<.001	.009	3	7
HNSC	LCP1 →	+0.547	+0.372	<.001	.006	3	7
HNSC	NFATC2 →	+0.541	+0.390	<.001	.009	3	7
BRCA	RASSF2 →	+0.500	+0.164	<.001	<.001	3	7
HNSC	ELMO1 →	+0.395	+0.215	<.001	.006	3	6
BRCA	MAP4K1 →	+0.560	+0.127	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 9,855 associations by consensus.

HSF5 vs LCP2 — UCEC

Explore this scatter interactively →