HSF2

Across TCGA patient cohorts, HSF2 RNA expression is significantly associated with the protein abundance of many other proteins, with 16,113 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible HSF2-associated proteins across cancer lineages are VTA1, PHF10, and SCAF8. Each is linked with HSF2 in more than 6 cancer types. Because this analysis shows association rather than direction, both HSF2-to-partner and partner-to-HSF2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, HSF2 versus VTA1 in OV, with a Pearson correlation of 0.47.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (HSF2→partner) and Y-score (partner→HSF2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	VTA1 →	+0.290	+0.464	<.001	<.001	3	6
OV	PHF10 →	+0.468	+0.631	<.001	.003	3	6
BRCA	SCAF8 →	+0.202	+0.412	.001	.001	3	6
GBM	CDC40 →	+0.277	+0.646	.003	<.001	2	7
GBM	HDDC2 →	+0.410	+0.634	<.001	<.001	3	6
OV	MAP3K4 →	+0.264	+0.543	.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 16,113 associations by consensus.

HSF2 vs VTA1 — OV

Explore this scatter interactively →