HSF2

Across TCGA patient cohorts, HSF2 protein abundance is significantly associated with the RNA expression of many other genes, with 5,739 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible HSF2-associated genes across cancer lineages are ARFGEF3, CDCA7L, and RNA5SP46. Each is linked with HSF2 in more than 1 cancer types. Because this analysis shows association rather than direction, both HSF2-to-partner and partner-to-HSF2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, HSF2 versus ARFGEF3 in LUAD, with a Pearson correlation of 0.53.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (HSF2→partner) and Y-score (partner→HSF2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	ARFGEF3 →	+1.161	+0.552	.008	.006	3	2
LSCC	CDCA7L →	+1.366	+0.964	<.001	<.001	3	2
BRCA	RNA5SP46 →	+0.804	+0.497	.001	.005	3	2
LSCC	CEP43 →	+0.634	+0.678	.002	.002	3	2
LUAD	LINC02036 →	+0.992	+0.597	.002	.001	3	2
LSCC	TSPY26P →	+1.311	+0.726	.001	.006	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,739 associations by consensus.

HSF2 vs ARFGEF3 — LUAD

Explore this scatter interactively →