HSF1

RNA expression — cross-omics
Cross-omicsRNA → FUNCTION-RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, HSF1 RNA expression is significantly associated with the go_rna of many other GO terms, with 2,992 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible HSF1-associated GO terms across cancer lineages are Cellular response to salt, Response to sodium arsenite, and Cellular response to sodium arsenite. Each is linked with HSF1 in more than 14 cancer types. Because this analysis shows association rather than direction, both HSF1-to-partner and partner-to-HSF1 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (HSF1→partner) and Y-score (partner→HSF1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner GO termX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
BONECellular response to salt →+0.219+1.286<.001<.001315
BONEResponse to sodium arsenite →+0.188+1.060.005<.001314
BONECellular response to sodium arsenite →+0.214+1.041<.001.001312
BONETranscription pausing by RNA polymerase II →+0.150+0.719<.001<.001312
BONEmiRNA-mediated gene silencing by mRNA destabilization →+0.123+0.689.003.003211
BONENucleosome disassembly →+0.184+1.004<.001<.001310
Each partner links to its Q-omics profile. Showing the 6 strongest of 2,992 associations by consensus.

Exploration