HSDL2

Across TCGA patient cohorts, HSDL2 protein abundance is significantly associated with the RNA expression of many other genes, with 18,505 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible HSDL2-associated genes across cancer lineages are ALAD, CTHRC1, and LDHD. Each is linked with HSDL2 in more than 6 cancer types. Because this analysis shows association rather than direction, both HSDL2-to-partner and partner-to-HSDL2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, HSDL2 versus ALAD in BRCA, with a Pearson correlation of 0.32.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (HSDL2→partner) and Y-score (partner→HSDL2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	ALAD →	+0.615	+0.461	<.001	<.001	3	7
GBM	CTHRC1 →	-1.119	-0.383	.002	<.001	3	6
UCEC	LDHD →	+1.124	+0.404	<.001	.002	3	6
BRCA	PRR11 →	-0.848	-0.346	<.001	<.001	3	6
BRCA	ABAT →	+1.406	+0.427	<.001	<.001	3	6
BRCA	AUH →	+0.475	+0.409	.002	.002	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 18,505 associations by consensus.

HSDL2 vs ALAD — BRCA

Explore this scatter interactively →