HSDL2

Across TCGA cell cohorts, HSDL2 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,299 significant associations in total. SOFT_TISSUE shows the largest number of these associations.

The most reproducible HSDL2-associated GO terms across cancer lineages are Proteasome regulatory particle assembly, Immunoglobulin heavy chain V-D-J recombination, and Positive regulation of mRNA 3'-end processing. Each is linked with HSDL2 in more than 12 cancer types. Because this analysis shows association rather than direction, both HSDL2-to-partner and partner-to-HSDL2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Proteasome regulatory particle assembly grouped by HSDL2-low versus HSDL2-high in SKIN.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (HSDL2→partner) and Y-score (partner→HSDL2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKIN	Proteasome regulatory particle assembly →	+0.141	+0.773	<.001	<.001	3	13
OVARY	Immunoglobulin heavy chain V-D-J recombination →	+0.175	+0.988	<.001	<.001	3	11
PANCREAS	Positive regulation of mRNA 3'-end processing →	+0.136	+0.892	<.001	<.001	3	10
OVARY	Positive regulation of chromosome condensation →	+0.181	+0.878	<.001	<.001	2	11
PANCREAS	Protein localization to kinetochore →	+0.144	+0.911	<.001	<.001	3	9
BREAST	Regulation of chromosome condensation →	+0.157	+0.950	.002	<.001	3	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,299 associations by consensus.

Proteasome regulatory particle assembly by HSDL2 expression — SKIN

Explore this box plot interactively →