HSDL1

Across TCGA cell cohorts, HSDL1 RNA expression is significantly associated with the go_rna of many other GO terms, with 5,077 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible HSDL1-associated GO terms across cancer lineages are Positive regulation of organelle assembly, Protein localization to cilium, and Positive regulation of double-strand break repair. Each is linked with HSDL1 in more than 15 cancer types. Because this analysis shows association rather than direction, both HSDL1-to-partner and partner-to-HSDL1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Positive regulation of organelle assembly grouped by HSDL1-low versus HSDL1-high in SOFT_TISSUE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (HSDL1→partner) and Y-score (partner→HSDL1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SOFT_TISSUE	Positive regulation of organelle assembly →	+0.074	+0.703	<.001	<.001	3	16
UPPER_AERODIGESTIVE_TRACT	Protein localization to cilium →	+0.069	+1.147	<.001	<.001	3	14
OESOPHAGUS	Positive regulation of double-strand break repair →	+0.073	+1.048	.008	<.001	2	15
LUNG_SCLC	Nuclear RNA surveillance →	+0.089	+0.664	<.001	.005	3	14
SOFT_TISSUE	Telomere maintenance via telomerase →	+0.106	+0.708	<.001	<.001	3	13
BREAST	Centrosome cycle →	+0.074	+0.807	<.001	<.001	3	13

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,077 associations by consensus.

Positive regulation of organelle assembly by HSDL1 expression — SOFT_TISSUE

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