HSD3BP2

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, HSD3BP2 mutation is significantly associated with the RNA expression of many other genes, with 364 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible HSD3BP2-associated genes across cancer lineages are RN7SKP149, UNGP1, and SNX3P1Y. Each is linked with HSD3BP2 in more than 1 cancer types. Because this analysis shows association rather than direction, both HSD3BP2-to-partner and partner-to-HSD3BP2 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (HSD3BP2→partner) and Y-score (partner→HSD3BP2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
LUADRN7SKP149 →+0.100+4.526<.001.00432
LUADUNGP1 →+0.035+2.815<.001.00832
UCECSNX3P1Y →+0.137+5.019<.001.00132
UCECMIR615 →+0.272+2.547.001.00932
UCECCAPZA1P3 →+0.170+2.200.003.00632
UCECCYCSP44 →+0.235+2.963<.001<.00132
Each partner links to its Q-omics profile. Showing the 6 strongest of 364 associations by consensus.

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