Across TCGA patient cohorts, HSD3BP2 mutation is significantly associated with the immune_cell of many other genes, with 5 significant associations in total. COAD shows the largest number of these associations.

The most reproducible HSD3BP2-associated genes across cancer lineages are Platelets, Adipocytes, and CD4+ memory T-cells. Each is linked with HSD3BP2 in more than 1 cancer types. Because this analysis shows association rather than direction, both HSD3BP2-to-partner and partner-to-HSD3BP2 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (HSD3BP2→partner) and Y-score (partner→HSD3BP2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	Platelets →	+0.020	+2.624	.005	.037	3	2
COAD	Adipocytes →	+0.030	+2.431	.047	.048	3	1
COAD	CD4+ memory T-cells →	+0.016	+2.958	.023	.021	3	1
UCEC	pDC →	+0.063	+3.008	.007	.019	3	1
UCEC	Th2 cells →	+0.252	+3.010	.003	.019	3	1

Each partner links to its Q-omics profile. Showing the 5 strongest of 5 associations by consensus.

Exploration

HSD3BP2 survival (RNA) · tumor vs normal (RNA) · all HSD3BP2 data types