HSD3B7

Across TCGA patient cohorts, HSD3B7 protein abundance is significantly associated with the RNA expression of many other genes, with 21,270 significant associations in total. GBM shows the largest number of these associations.

The most reproducible HSD3B7-associated genes across cancer lineages are MEFV, FCGR3B, and SOD2. Each is linked with HSD3B7 in more than 5 cancer types. Because this analysis shows association rather than direction, both HSD3B7-to-partner and partner-to-HSD3B7 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, HSD3B7 versus MEFV in GBM, with a Pearson correlation of 0.38.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (HSD3B7→partner) and Y-score (partner→HSD3B7) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	MEFV →	+0.700	+0.350	<.001	.001	3	6
HNSC	FCGR3B →	+1.359	+0.704	<.001	.007	3	6
OV	SOD2 →	+1.179	+0.986	<.001	.001	3	5
GBM	FPR2 →	+1.359	+0.390	<.001	<.001	3	5
COAD	VNN3 →	+0.598	+1.908	<.001	<.001	3	5
OV	VNN2 →	+1.202	+0.887	<.001	.003	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 21,270 associations by consensus.

HSD3B7 vs MEFV — GBM

Explore this scatter interactively →