HSD3B7

Across TCGA cell cohorts, HSD3B7 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,374 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible HSD3B7-associated GO terms across cancer lineages are B cell chemotaxis, Fatty acid catabolic process, and Regulation of amino acid biosynthetic process. Each is linked with HSD3B7 in more than 12 cancer types. Because this analysis shows association rather than direction, both HSD3B7-to-partner and partner-to-HSD3B7 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, B cell chemotaxis grouped by HSD3B7-low versus HSD3B7-high in URINARY_TRACT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (HSD3B7→partner) and Y-score (partner→HSD3B7) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
URINARY_TRACT	B cell chemotaxis →	+1.442	+2.318	<.001	.001	2	13
UPPER_AERODIGESTIVE_TRACT	Fatty acid catabolic process →	+0.097	+1.223	.001	.009	3	12
BONE	Regulation of amino acid biosynthetic process →	+0.183	+2.150	<.001	<.001	3	11
BLOOD_Leukemia	Negative regulation of cellular response to hypoxia →	+0.091	+1.051	<.001	<.001	3	10
SOFT_TISSUE	Positive regulation of G2/MI transition of meiotic cell cycle →	-0.193	-1.778	<.001	<.001	3	9
BONE	Regulation of amino acid metabolic process →	+0.154	+1.493	<.001	<.001	3	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,374 associations by consensus.

B cell chemotaxis by HSD3B7 expression — URINARY_TRACT

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