Across TCGA patient cohorts, HSD3B2 mutation is significantly associated with the RNA expression of many other genes, with 1,440 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible HSD3B2-associated genes across cancer lineages are FCER1A, CKS1B, and SSX2B. Each is linked with HSD3B2 in more than 2 cancer types. Because this analysis shows association rather than direction, both HSD3B2-to-partner and partner-to-HSD3B2 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (HSD3B2→partner) and Y-score (partner→HSD3B2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	FCER1A →	-0.823	-3.676	.001	.001	3	3
SKCM	CKS1B →	+0.466	+3.497	.002	.002	3	3
BRCA	SSX2B →	+0.242	+5.347	<.001	.006	3	2
UCEC	DFFA →	+0.502	+3.818	<.001	<.001	3	2
UCEC	PKN3 →	+0.692	+2.425	<.001	.002	3	2
SKCM	BAALC →	-1.669	-3.087	.001	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,440 associations by consensus.

Exploration

HSD3B2 survival (RNA) · tumor vs normal (RNA) · all HSD3B2 data types