Across TCGA cell cohorts, HSD3B2 RNA expression is significantly associated with the go_rna of many other GO terms, with 428 significant associations in total. UPPER_AERODIGESTIVE_TRACT shows the largest number of these associations.

The most reproducible HSD3B2-associated GO terms across cancer lineages are Adenylate cyclase-modulating G protein-coupled receptor signaling pathway, Response to methylglyoxal, and Methylglyoxal catabolic process. Each is linked with HSD3B2 in more than 3 cancer types. Because this analysis shows association rather than direction, both HSD3B2-to-partner and partner-to-HSD3B2 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (HSD3B2→partner) and Y-score (partner→HSD3B2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	Adenylate cyclase-modulating G protein-coupled receptor signaling pathway →	-0.033	-0.016	<.001	.002	3	4
UPPER_AERODIGESTIVE_TRACT	Response to methylglyoxal →	+0.106	+0.029	.003	.005	3	3
UPPER_AERODIGESTIVE_TRACT	Methylglyoxal catabolic process →	+0.092	+0.019	.002	.009	3	3
UPPER_AERODIGESTIVE_TRACT	Cellular response to methylglyoxal →	+0.106	+0.029	.003	.005	3	3
LUNG_NSCLC_LUSC	T cell chemotaxis →	-0.481	-0.065	.006	.008	3	3
UPPER_AERODIGESTIVE_TRACT	Cellular response to aldehyde →	+0.108	+0.028	.002	.007	2	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 428 associations by consensus.

Exploration

HSD3B2 survival (RNA) · tumor vs normal (RNA) · all HSD3B2 data types