Across TCGA patient cohorts, HSD3B1 RNA expression is significantly associated with the protein abundance of many other proteins, with 12,246 significant associations in total. GBM shows the largest number of these associations.

The most reproducible HSD3B1-associated proteins across cancer lineages are TRA2A_S100, PRPF4B_S294, and RER1_S95. Each is linked with HSD3B1 in more than 2 cancer types. Because this analysis shows association rather than direction, both HSD3B1-to-partner and partner-to-HSD3B1 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (HSD3B1→partner) and Y-score (partner→HSD3B1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	TRA2A_S100 →	-1.319	-0.396	<.001	.003	3	3
PDAC	PRPF4B_S294 →	-0.669	-0.707	.007	<.001	3	3
PDAC	RER1_S95 →	-0.547	-0.618	.004	.001	3	3
PDAC	RPS19 →	-0.364	-0.519	<.001	.004	3	3
GBM	SLC4A7_S84 →	-0.753	-0.236	<.001	.002	3	3
GBM	NCF4 →	-0.621	-0.133	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 12,246 associations by consensus.

Exploration

HSD3B1 survival (RNA) · tumor vs normal (RNA) · all HSD3B1 data types