Across TCGA patient cohorts, HSD3B1 RNA expression is significantly associated with the go_rna of many other GO terms, with 6,554 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible HSD3B1-associated GO terms across cancer lineages are Glucan metabolic process, Developmental growth involved in morphogenesis, and Regulation of transmembrane receptor protein serine/threonine kinase signaling pathway. Each is linked with HSD3B1 in more than 9 cancer types. Because this analysis shows association rather than direction, both HSD3B1-to-partner and partner-to-HSD3B1 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (HSD3B1→partner) and Y-score (partner→HSD3B1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
ESCA	Glucan metabolic process →	+0.035	+0.254	<.001	.006	3	10
TGCT	Developmental growth involved in morphogenesis →	+0.028	+0.653	<.001	<.001	3	9
TGCT	Regulation of transmembrane receptor protein serine/threonine kinase signaling pathway →	+0.036	+0.560	<.001	<.001	3	8
STAD	Regulation of mitochondrial fission →	+0.081	+0.230	<.001	<.001	3	8
TGCT	Regulation of cholesterol metabolic process →	+0.053	+0.543	<.001	<.001	3	8
STAD	Thioester metabolic process →	+0.047	+0.179	<.001	<.001	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,554 associations by consensus.

Exploration

HSD3B1 survival (RNA) · tumor vs normal (RNA) · all HSD3B1 data types