Across TCGA patient cohorts, HSD3B1 protein abundance is significantly associated with the RNA expression of many other genes, with 255 significant associations in total. PDAC shows the largest number of these associations.

The most reproducible HSD3B1-associated genes across cancer lineages are PRODH, CDC25B, and USB1. Each is linked with HSD3B1 in more than 1 cancer types. Because this analysis shows association rather than direction, both HSD3B1-to-partner and partner-to-HSD3B1 results are reported.

Each partner links to its own Q-omics profile.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (HSD3B1→partner) and Y-score (partner→HSD3B1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PDAC	PRODH →	+0.710	+0.475	.007	<.001	3	1
PDAC	CDC25B →	+0.613	+0.306	.001	.007	3	1
PDAC	USB1 →	+0.451	+0.364	.004	.009	3	1
PDAC	HOMER2 →	-1.508	-0.368	.009	.007	3	1
PDAC	PBX4 →	+0.853	+0.334	.001	.002	3	1
PDAC	PDLIM1 →	+0.628	+0.426	.003	.002	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 255 associations by consensus.

Exploration

HSD3B1 survival (RNA) · tumor vs normal (RNA) · all HSD3B1 data types