Across TCGA cell cohorts, HSD3B1 RNA expression is significantly associated with the go_rna of many other GO terms, with 450 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible HSD3B1-associated GO terms across cancer lineages are Late endosome to vacuole transport via multivesicular body sorting pathway, Protein targeting to membrane, and Phosphatidylcholine biosynthetic process. Each is linked with HSD3B1 in more than 3 cancer types. Because this analysis shows association rather than direction, both HSD3B1-to-partner and partner-to-HSD3B1 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (HSD3B1→partner) and Y-score (partner→HSD3B1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
URINARY_TRACT	Late endosome to vacuole transport via multivesicular body sorting pathway →	+0.071	+2.134	<.001	<.001	3	4
URINARY_TRACT	Protein targeting to membrane →	+0.069	+2.701	<.001	.003	3	4
URINARY_TRACT	Phosphatidylcholine biosynthetic process →	+0.171	+2.916	.001	.006	3	3
URINARY_TRACT	Positive regulation of amyloid precursor protein catabolic process →	+0.087	+2.068	<.001	.001	3	3
LARGE_INTESTINE	Type B pancreatic cell proliferation →	+0.143	+1.809	.007	.001	3	3
LARGE_INTESTINE	C21-steroid hormone biosynthetic process →	-0.218	-2.367	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 450 associations by consensus.

Exploration

HSD3B1 survival (RNA) · tumor vs normal (RNA) · all HSD3B1 data types