HSD17B7P2

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, HSD17B7P2 mutation is significantly associated with the RNA expression of many other genes, with 323 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible HSD17B7P2-associated genes across cancer lineages are TSPY16P, RNU5A-7P, and MIR548B. Each is linked with HSD17B7P2 in more than 1 cancer types. Because this analysis shows association rather than direction, both HSD17B7P2-to-partner and partner-to-HSD17B7P2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, TSPY16P grouped by HSD17B7P2-low versus HSD17B7P2-high in LIHC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (HSD17B7P2→partner) and Y-score (partner→HSD17B7P2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
LIHCTSPY16P →+0.113+6.305<.001.00132
LIHCRNU5A-7P →+0.435+5.186<.001.00732
BLCAMIR548B →+0.283+5.814<.001.00132
SKCMRN7SKP83 →+0.220+2.992<.001.00932
SKCMRNA5SP165 →+0.432+3.993<.001<.00132
LUADOR5T3 →+0.072+4.418<.001.00632
Each partner links to its Q-omics profile. Showing the 6 strongest of 323 associations by consensus.

TSPY16P by HSD17B7P2 expression — LIHC

Box plot of TSPY16P in HSD17B7P2-low vs HSD17B7P2-high samples in LIHC.

Explore this box plot interactively →

Exploration