HSD17B7

Across TCGA cell cohorts, HSD17B7 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,111 significant associations in total. SOFT_TISSUE shows the largest number of these associations.

The most reproducible HSD17B7-associated GO terms across cancer lineages are Farnesyl diphosphate biosynthetic process, Farnesyl diphosphate metabolic process, and Sterol biosynthetic process. Each is linked with HSD17B7 in more than 19 cancer types. Because this analysis shows association rather than direction, both HSD17B7-to-partner and partner-to-HSD17B7 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Farnesyl diphosphate biosynthetic process grouped by HSD17B7-low versus HSD17B7-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (HSD17B7→partner) and Y-score (partner→HSD17B7) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	Farnesyl diphosphate biosynthetic process →	+0.201	+1.271	<.001	<.001	3	20
BONE	Farnesyl diphosphate metabolic process →	+0.178	+1.522	<.001	<.001	3	20
OESOPHAGUS	Sterol biosynthetic process →	+0.220	+1.838	<.001	<.001	3	18
BONE	Secondary alcohol biosynthetic process →	+0.231	+1.644	<.001	<.001	3	18
BONE	Cholesterol biosynthetic process →	+0.231	+1.644	<.001	<.001	3	18
BONE	Farnesyl diphosphate biosynthetic process, mevalonate pathway →	+0.231	+1.595	<.001	<.001	3	18

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,111 associations by consensus.

Farnesyl diphosphate biosynthetic process by HSD17B7 expression — BONE

Explore this box plot interactively →