HSD17B4

Across TCGA patient cohorts, HSD17B4 RNA expression is significantly associated with the protein abundance of many other proteins, with 14,204 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible HSD17B4-associated proteins across cancer lineages are YTHDC2, CLINT1, and HINT1. Each is linked with HSD17B4 in more than 5 cancer types. Because this analysis shows association rather than direction, both HSD17B4-to-partner and partner-to-HSD17B4 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, HSD17B4 versus YTHDC2 in OV, with a Pearson correlation of 0.50.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (HSD17B4→partner) and Y-score (partner→HSD17B4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	YTHDC2 →	+0.265	+0.459	<.001	<.001	3	6
OV	CLINT1 →	+0.235	+0.483	.006	.002	3	6
OV	HINT1 →	+0.354	+0.497	.002	.003	3	6
BRCA	PKP4 →	+0.461	+0.698	<.001	<.001	3	5
CCRCC	HSD17B4_T265 →	+0.566	+0.471	<.001	<.001	3	5
BRCA	MOCS2 →	+0.432	+0.653	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 14,204 associations by consensus.

HSD17B4 vs YTHDC2 — OV

Explore this scatter interactively →