HSD17B4

Across TCGA patient cohorts, HSD17B4 protein abundance is significantly associated with the protein abundance of many other proteins, with 30,177 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible HSD17B4-associated proteins across cancer lineages are ACAA1, SCP2, and HSD17B4_S294. Each is linked with HSD17B4 in more than 7 cancer types. Because this analysis shows association rather than direction, both HSD17B4-to-partner and partner-to-HSD17B4 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, HSD17B4 versus ACAA1 in UCEC, with a Pearson correlation of 0.45.

protein abundance associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (HSD17B4→partner) and Y-score (partner→HSD17B4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	ACAA1 →	+0.480	+0.435	<.001	<.001	3	8
UCEC	SCP2 →	+0.379	+0.465	<.001	<.001	3	8
PDAC	HSD17B4_S294 →	+1.248	+0.514	.003	<.001	3	8
CCRCC	HSD17B4_T265 →	+0.605	+0.399	<.001	<.001	3	8
GBM	GNPAT →	+0.436	+0.485	<.001	<.001	3	7
BRCA	MCCC2 →	+0.441	+0.264	.001	.002	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 30,177 associations by consensus.

HSD17B4 vs ACAA1 — UCEC

Explore this scatter interactively →