HSD17B2

Across TCGA patient cohorts, HSD17B2 RNA expression is significantly associated with the protein abundance of many other proteins, with 9,324 significant associations in total. LUAD shows the largest number of these associations.

The most reproducible HSD17B2-associated proteins across cancer lineages are RALGAPA2, RDH10, and GSDMB. Each is linked with HSD17B2 in more than 3 cancer types. Because this analysis shows association rather than direction, both HSD17B2-to-partner and partner-to-HSD17B2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, HSD17B2 versus RALGAPA2 in LSCC, with a Pearson correlation of 0.39.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (HSD17B2→partner) and Y-score (partner→HSD17B2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	RALGAPA2 →	+0.361	+0.847	<.001	<.001	3	4
BRCA	RDH10 →	+0.790	+0.659	<.001	<.001	3	4
LUAD	GSDMB →	+0.841	+0.778	.001	<.001	3	4
LSCC	BCAS1 →	+0.915	+0.448	<.001	.001	3	4
LSCC	DHRS3 →	+0.629	+0.467	<.001	<.001	3	4
COAD	RAB27B →	+0.795	+0.975	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 9,324 associations by consensus.

HSD17B2 vs RALGAPA2 — LSCC

Explore this scatter interactively →