HSD17B1P1

Across TCGA pan-cancer cohorts, HSD17B1P1 mass-spec protein is linked to patient survival in 2 of 34 cancer types, making it a survival-associated HSD17B1P1 data layer compared with 26 for mass-spec protein.

The strongest signal is observed in pancreatic ductal adenocarcinoma (PDAC), where higher HSD17B1P1 mass-spec protein is associated with better disease-free survival. In most high-consensus cancer types, elevated HSD17B1P1 expression acts as an unfavorable survival marker, although some lineages such as PDAC show a favorable association.

PDAC and LUAD are the cancer types where HSD17B1P1 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
PDAC	DFS	Quartile	II,III,IV	0.875	0.431	.012	17	view →
LUAD	OS	Quartile	II,III,IV	0.281	0.736	.044	2	view →

Pink = unfavorable, green = favorable. Showing the 2 strongest of 2 lineages.

HSD17B1P1–PDAC (DFS)

Open the PDAC breakdown →