HSD17B13

Across TCGA patient cohorts, HSD17B13 protein abundance is significantly associated with the protein abundance of many other proteins, with 3,652 significant associations in total. LUAD shows the largest number of these associations.

The most reproducible HSD17B13-associated proteins across cancer lineages are ALDH1L1, BCAS1_S552, and ACTN2. Each is linked with HSD17B13 in more than 1 cancer types. Because this analysis shows association rather than direction, both HSD17B13-to-partner and partner-to-HSD17B13 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, HSD17B13 versus ALDH1L1 in CCRCC, with a Pearson correlation of 0.62.

protein abundance associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (HSD17B13→partner) and Y-score (partner→HSD17B13) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CCRCC	ALDH1L1 →	+1.004	+1.681	.002	.003	3	2
LUAD	BCAS1_S552 →	+1.277	+0.566	.001	<.001	3	2
LUAD	ACTN2 →	+0.404	+0.481	<.001	<.001	3	2
LUAD	ADAMTS2 →	-0.464	-0.584	<.001	.001	3	2
LSCC	CARMIL1_S1315 →	+0.430	+0.521	.002	.001	3	2
LUAD	ADIRF →	+0.523	+0.717	<.001	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,652 associations by consensus.

HSD17B13 vs ALDH1L1 — CCRCC

Explore this scatter interactively →