HSD17B12

Across TCGA patient cohorts, HSD17B12 protein abundance is significantly associated with the RNA expression of many other genes, with 7,575 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible HSD17B12-associated genes across cancer lineages are NR3C1, IFIT2, and NES. Each is linked with HSD17B12 in more than 2 cancer types. Because this analysis shows association rather than direction, both HSD17B12-to-partner and partner-to-HSD17B12 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, HSD17B12 versus NR3C1 in UCEC, with a Pearson correlation of -0.34.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (HSD17B12→partner) and Y-score (partner→HSD17B12) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	NR3C1 →	-0.643	-0.488	<.001	.001	3	3
HNSC	IFIT2 →	-1.130	-0.300	.004	.005	3	3
OV	NES →	-0.948	-0.357	<.001	<.001	3	3
BRCA	RERG →	-1.853	-0.436	<.001	<.001	3	3
HNSC	HERC5 →	-0.914	-0.314	.002	.002	3	3
COAD	DPT →	-1.141	-0.315	.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,575 associations by consensus.

HSD17B12 vs NR3C1 — UCEC

Explore this scatter interactively →