HSD17B1

Across TCGA patient cohorts, HSD17B1 RNA expression is significantly associated with the protein abundance of many other proteins, with 8,619 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible HSD17B1-associated proteins across cancer lineages are AOX1, USP10_S547, and RALY_S135. Each is linked with HSD17B1 in more than 3 cancer types. Because this analysis shows association rather than direction, both HSD17B1-to-partner and partner-to-HSD17B1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, HSD17B1 versus AOX1 in LSCC, with a Pearson correlation of -0.48.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (HSD17B1→partner) and Y-score (partner→HSD17B1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	AOX1 →	-0.427	-0.516	<.001	<.001	3	4
LUAD	USP10_S547 →	+0.688	+0.342	<.001	.001	3	3
LSCC	RALY_S135 →	-0.297	-0.574	.007	.001	3	3
LSCC	NDRG1 →	+0.755	+0.685	<.001	<.001	3	3
HNSC	NFATC2_S217 →	-0.452	-0.653	.001	<.001	3	3
GBM	P2RY8_S324 →	-0.680	-0.215	.007	.003	2	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 8,619 associations by consensus.

HSD17B1 vs AOX1 — LSCC

Explore this scatter interactively →