HSD11B1

Across TCGA patient cohorts, HSD11B1 RNA expression is significantly associated with the protein abundance of many other proteins, with 18,872 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible HSD11B1-associated proteins across cancer lineages are CORO1A, DOCK2, and FYB1. Each is linked with HSD11B1 in more than 8 cancer types. Because this analysis shows association rather than direction, both HSD11B1-to-partner and partner-to-HSD11B1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, HSD11B1 versus CORO1A in UCEC, with a Pearson correlation of 0.43.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (HSD11B1→partner) and Y-score (partner→HSD11B1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	CORO1A →	+0.591	+1.330	.002	<.001	3	9
GBM	DOCK2 →	+0.578	+1.180	<.001	<.001	3	9
UCEC	FYB1 →	+0.736	+1.272	<.001	<.001	3	9
LSCC	ARHGEF6 →	+0.423	+0.790	<.001	<.001	3	9
OV	TBC1D2B →	+0.340	+1.249	<.001	.002	3	9
UCEC	SASH3 →	+0.490	+1.062	<.001	.002	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 18,872 associations by consensus.

HSD11B1 vs CORO1A — UCEC

Explore this scatter interactively →