HSD11B1

Across TCGA cell cohorts, HSD11B1 RNA expression is significantly associated with the RNA expression of many other genes, with 3,966 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible HSD11B1-associated genes across cancer lineages are LAMB3, CSF2, and IL1A. Each is linked with HSD11B1 in more than 8 cancer types. Because this analysis shows association rather than direction, both HSD11B1-to-partner and partner-to-HSD11B1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, HSD11B1 versus LAMB3 in KIDNEY, with a Pearson correlation of 0.61.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (HSD11B1→partner) and Y-score (partner→HSD11B1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
KIDNEY	LAMB3 →	+2.663	+0.339	.001	.008	1	9
LUNG_NSCLC_LUAD	CSF2 →	+1.952	+0.752	<.001	<.001	3	5
PANCREAS	IL1A →	+2.099	+1.231	<.001	.001	3	5
BLOOD_Lymphoma	TNFRSF9 →	+1.625	+0.820	<.001	.002	3	5
LUNG_NSCLC_LUAD	CATSPER1 →	+1.946	+0.613	<.001	<.001	3	4
PANCREAS	SERPINB2 →	+2.906	+1.670	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,966 associations by consensus.

HSD11B1 vs LAMB3 — KIDNEY

Explore this scatter interactively →