Across TCGA patient cohorts, HSBP1 RNA expression is significantly associated with the protein abundance of many other proteins, with 11,235 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible HSBP1-associated proteins across cancer lineages are WWP2, AP1G1, and CFDP1. Each is linked with HSBP1 in more than 6 cancer types. Because this analysis shows association rather than direction, both HSBP1-to-partner and partner-to-HSBP1 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (HSBP1→partner) and Y-score (partner→HSBP1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	WWP2 →	+0.350	+0.321	<.001	.001	3	7
OV	AP1G1 →	+0.264	+0.720	.003	.001	3	6
OV	CFDP1 →	+0.462	+0.763	.001	<.001	3	6
HNSC	CMIP →	+0.480	+0.525	<.001	<.001	3	6
OV	HSDL1 →	+0.465	+0.734	<.001	<.001	3	6
OV	USP10 →	+0.317	+0.605	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 11,235 associations by consensus.

Exploration

HSBP1 survival (RNA) · tumor vs normal (RNA) · all HSBP1 data types