Across TCGA patient cohorts, HSBP1 protein abundance is significantly associated with the RNA expression of many other genes, with 9,255 significant associations in total. HNSC shows the largest number of these associations.

The most reproducible HSBP1-associated genes across cancer lineages are ZBP1, FCRL3, and GBP4. Each is linked with HSBP1 in more than 4 cancer types. Because this analysis shows association rather than direction, both HSBP1-to-partner and partner-to-HSBP1 results are reported.

Each partner links to its own Q-omics profile.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (HSBP1→partner) and Y-score (partner→HSBP1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	ZBP1 →	-1.031	-0.283	<.001	<.001	3	5
UCEC	FCRL3 →	-0.712	-0.264	.001	.001	3	5
HNSC	GBP4 →	-1.263	-0.325	<.001	<.001	3	5
BRCA	CXCR2P1 →	-1.517	-0.259	<.001	<.001	3	5
BRCA	IFNG →	-1.097	-0.272	<.001	.001	3	4
UCEC	IFT43 →	+0.547	+0.363	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 9,255 associations by consensus.

Exploration

HSBP1 survival (RNA) · tumor vs normal (RNA) · all HSBP1 data types