Across TCGA patient cohorts, HSBP1 mutation is significantly associated with the RNA expression of many other genes, with 23 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible HSBP1-associated genes across cancer lineages are NAMPTP2, RNA5SP419, and OR2M4. Each is linked with HSBP1 in more than 1 cancer types. Because this analysis shows association rather than direction, both HSBP1-to-partner and partner-to-HSBP1 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (HSBP1→partner) and Y-score (partner→HSBP1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	NAMPTP2 →	+0.089	+5.027	<.001	.004	3	2
UCEC	RNA5SP419 →	+1.928	+4.661	<.001	.004	3	2
UCEC	OR2M4 →	+0.203	+5.146	<.001	.001	3	1
BLCA	MIR548AV →	+0.472	+7.640	<.001	.009	3	1
UCEC	RNU6-1082P →	+0.789	+6.136	<.001	<.001	3	1
UCEC	OR6K3 →	+0.253	+5.567	<.001	<.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 23 associations by consensus.

Exploration

HSBP1 survival (RNA) · tumor vs normal (RNA) · all HSBP1 data types