HS6ST3

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, HS6ST3 mutation is significantly associated with the RNA expression of many other genes, with 2,857 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible HS6ST3-associated genes across cancer lineages are CINP, ACTR5, and ANAPC15. Each is linked with HS6ST3 in more than 1 cancer types. Because this analysis shows association rather than direction, both HS6ST3-to-partner and partner-to-HS6ST3 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (HS6ST3→partner) and Y-score (partner→HS6ST3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
UCECCINP →+0.361+4.053<.001<.00132
UCECACTR5 →+0.420+3.475.001.00232
SKCMANAPC15 →+0.557+3.919<.001<.00132
UCECTTC1 →+0.398+3.483.001.00232
UCECSTMN1 →+0.716+2.906.008.00232
SKCMTAS2R7 →+0.018+2.832<.001<.00132
Each partner links to its Q-omics profile. Showing the 6 strongest of 2,857 associations by consensus.

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