Across TCGA cell cohorts, HS6ST3 RNA expression is significantly associated with the go_rna of many other GO terms, with 1,499 significant associations in total. BREAST shows the largest number of these associations.

The most reproducible HS6ST3-associated GO terms across cancer lineages are Positive regulation of mRNA catabolic process, Negative regulation of blood-brain barrier permeability, and Dorsal/ventral pattern formation. Each is linked with HS6ST3 in more than 4 cancer types. Because this analysis shows association rather than direction, both HS6ST3-to-partner and partner-to-HS6ST3 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (HS6ST3→partner) and Y-score (partner→HS6ST3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UPPER_AERODIGESTIVE_TRACT	Positive regulation of mRNA catabolic process →	+0.044	+0.085	.002	.003	3	5
BREAST	Negative regulation of blood-brain barrier permeability →	-0.165	-0.881	.007	.002	3	5
OVARY	Dorsal/ventral pattern formation →	-0.064	-0.292	<.001	.008	3	5
BREAST	Vesicle targeting, to, from or within Golgi →	+0.054	+0.858	.001	.003	3	4
BREAST	Endothelial tube morphogenesis →	+0.064	+1.254	.007	<.001	3	4
SKIN	Negative regulation of peptidyl-threonine phosphorylation →	+0.114	+0.285	.001	.008	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,499 associations by consensus.

Exploration

HS6ST3 survival (RNA) · tumor vs normal (RNA) · all HS6ST3 data types