HS6ST2

protein abundance — cross-omics
Cross-omicsPROTEIN-MS → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, HS6ST2 protein abundance is significantly associated with the RNA expression of many other genes, with 2,393 significant associations in total. LUAD shows the largest number of these associations.

The most reproducible HS6ST2-associated genes across cancer lineages are C11orf96, RNA5SP227, and IGSF9B. Each is linked with HS6ST2 in more than 1 cancer types. Because this analysis shows association rather than direction, both HS6ST2-to-partner and partner-to-HS6ST2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, HS6ST2 versus C11orf96 in UCEC, with a Pearson correlation of 0.45.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (HS6ST2→partner) and Y-score (partner→HS6ST2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
UCECC11orf96 →+1.182+0.459.007.00632
UCECRNA5SP227 →+1.231+0.580<.001<.00132
LUADIGSF9B →+0.940+0.658.003<.00132
CCRCCSOD2 →-1.003-0.672.001<.00132
LUADSHE →+1.053+0.683<.001<.00132
LSCCNRARP →+0.992+0.763.001<.00132
Each partner links to its Q-omics profile. Showing the 6 strongest of 2,393 associations by consensus.

HS6ST2 vs C11orf96 — UCEC

Per-sample scatter of HS6ST2 vs C11orf96 in UCEC (Pearson r = 0.45).

Explore this scatter interactively →

Exploration