HS6ST1

Across TCGA patient cohorts, HS6ST1 RNA expression is significantly associated with the protein abundance of many other proteins, with 11,278 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible HS6ST1-associated proteins across cancer lineages are PSMB8, NONO, and SUDS3. Each is linked with HS6ST1 in more than 3 cancer types. Because this analysis shows association rather than direction, both HS6ST1-to-partner and partner-to-HS6ST1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, HS6ST1 versus PSMB8 in LSCC, with a Pearson correlation of -0.42.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (HS6ST1→partner) and Y-score (partner→HS6ST1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	PSMB8 →	-0.360	-0.710	<.001	<.001	3	4
LSCC	NONO →	+0.217	+0.757	<.001	<.001	3	4
LSCC	SUDS3 →	+0.248	+0.510	<.001	.002	3	4
HNSC	CASP1 →	-0.441	-0.714	<.001	<.001	3	4
HNSC	CASP4 →	-0.429	-0.689	<.001	<.001	3	4
HNSC	FAM114A2 →	-0.271	-0.840	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 11,278 associations by consensus.

HS6ST1 vs PSMB8 — LSCC

Explore this scatter interactively →