HS6ST1

Across TCGA cell cohorts, HS6ST1 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,271 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible HS6ST1-associated GO terms across cancer lineages are Regulation of stem cell population maintenance, Positive regulation of stem cell population maintenance, and Regulation of RNA splicing. Each is linked with HS6ST1 in more than 13 cancer types. Because this analysis shows association rather than direction, both HS6ST1-to-partner and partner-to-HS6ST1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of stem cell population maintenance grouped by HS6ST1-low versus HS6ST1-high in OVARY.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (HS6ST1→partner) and Y-score (partner→HS6ST1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OVARY	Regulation of stem cell population maintenance →	+0.084	+1.993	<.001	<.001	3	14
LUNG_SCLC	Positive regulation of stem cell population maintenance →	+0.090	+0.801	<.001	.005	2	14
BLOOD_Lymphoma	Regulation of RNA splicing →	+0.080	+1.631	<.001	<.001	3	12
BLOOD_Lymphoma	Negative regulation of RNA splicing →	+0.105	+1.291	<.001	<.001	3	12
OVARY	Regulation of G1/S transition of mitotic cell cycle →	+0.058	+1.671	<.001	.001	3	12
BLOOD_Lymphoma	Negative regulation of mRNA splicing, via spliceosome →	+0.111	+1.237	<.001	<.001	3	11

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,271 associations by consensus.

Regulation of stem cell population maintenance by HS6ST1 expression — OVARY

Explore this box plot interactively →