HS3ST5

Across TCGA cell cohorts, HS3ST5 RNA expression is significantly associated with the go_rna of many other GO terms, with 1,348 significant associations in total. SOFT_TISSUE shows the largest number of these associations.

The most reproducible HS3ST5-associated GO terms across cancer lineages are Organic acid transport, Carboxylic acid transport, and Transport across blood-brain barrier. Each is linked with HS3ST5 in more than 5 cancer types. Because this analysis shows association rather than direction, both HS3ST5-to-partner and partner-to-HS3ST5 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Organic acid transport grouped by HS3ST5-low versus HS3ST5-high in SKIN.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (HS3ST5→partner) and Y-score (partner→HS3ST5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKIN	Organic acid transport →	-0.046	-0.376	<.001	.007	3	5
SKIN	Carboxylic acid transport →	-0.046	-0.376	<.001	.007	3	5
BONE	Transport across blood-brain barrier →	-0.060	-0.713	.007	.008	3	5
SOFT_TISSUE	Regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway →	+0.089	+0.433	.007	.002	3	5
BONE	Vascular transport →	-0.060	-0.713	.007	.008	3	5
SOFT_TISSUE	Golgi vesicle transport →	+0.040	+0.382	<.001	.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,348 associations by consensus.

Organic acid transport by HS3ST5 expression — SKIN

Explore this box plot interactively →