HS3ST3B1

Across TCGA patient cohorts, HS3ST3B1 protein abundance is significantly associated with the RNA expression of many other genes, with 429 significant associations in total. GBM shows the largest number of these associations.

The most reproducible HS3ST3B1-associated genes across cancer lineages are IL9, OR10A5, and ACER2P1. Each is linked with HS3ST3B1 in more than 1 cancer types. Because this analysis shows association rather than direction, both HS3ST3B1-to-partner and partner-to-HS3ST3B1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, HS3ST3B1 versus IL9 in COAD, with a Pearson correlation of -0.81.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (HS3ST3B1→partner) and Y-score (partner→HS3ST3B1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	IL9 →	-0.250	-1.223	<.001	.001	3	1
COAD	OR10A5 →	-0.150	-1.223	<.001	.001	3	1
COAD	ACER2P1 →	-0.186	-1.223	<.001	.001	3	1
COAD	MIR601 →	-1.516	-1.223	.004	.001	2	2
COAD	PCDHA13 →	-0.040	-1.045	.007	.008	3	1
COAD	LINC00682 →	-0.046	-0.978	<.001	.008	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 429 associations by consensus.

HS3ST3B1 vs IL9 — COAD

Explore this scatter interactively →