HS3ST3B1

Across TCGA cell cohorts, HS3ST3B1 RNA expression is significantly associated with the RNA expression of many other genes, with 9,181 significant associations in total. BONE shows the largest number of these associations.

The most reproducible HS3ST3B1-associated genes across cancer lineages are HS3ST3A1, PLOD2, and PTPN12. Each is linked with HS3ST3B1 in more than 16 cancer types. Because this analysis shows association rather than direction, both HS3ST3B1-to-partner and partner-to-HS3ST3B1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, HS3ST3B1 versus HS3ST3A1 in KIDNEY, with a Pearson correlation of 0.77.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (HS3ST3B1→partner) and Y-score (partner→HS3ST3B1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
KIDNEY	HS3ST3A1 →	+3.223	+1.523	<.001	<.001	3	17
BLOOD_Lymphoma	PLOD2 →	+2.809	+2.209	<.001	<.001	3	6
BLOOD_Lymphoma	PTPN12 →	+1.301	+1.954	<.001	<.001	3	5
OESOPHAGUS	TMCC2 →	+1.201	+1.409	.001	<.001	3	5
OESOPHAGUS	ZG16B →	-1.769	-1.208	.005	.002	3	5
BLOOD_Lymphoma	NFIL3 →	+1.473	+1.491	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 9,181 associations by consensus.

HS3ST3B1 vs HS3ST3A1 — KIDNEY

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