HS3ST3B1

Across TCGA cell cohorts, HS3ST3B1 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,652 significant associations in total. BONE shows the largest number of these associations.

The most reproducible HS3ST3B1-associated GO terms across cancer lineages are Response to acetaldehyde, Cellular response to acetaldehyde, and Dendritic spine morphogenesis. Each is linked with HS3ST3B1 in more than 6 cancer types. Because this analysis shows association rather than direction, both HS3ST3B1-to-partner and partner-to-HS3ST3B1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Response to acetaldehyde grouped by HS3ST3B1-low versus HS3ST3B1-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (HS3ST3B1→partner) and Y-score (partner→HS3ST3B1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	Response to acetaldehyde →	+0.311	+1.665	<.001	<.001	3	7
BONE	Cellular response to acetaldehyde →	+0.311	+1.665	<.001	<.001	3	7
BONE	Dendritic spine morphogenesis →	-0.099	-1.523	.002	.007	3	7
SKIN	Negative regulation of dopamine receptor signaling pathway →	+0.968	+1.192	<.001	.001	3	7
BONE	Metanephric part of ureteric bud development →	+0.799	+2.269	.008	<.001	2	7
LUNG_SCLC	Regulation of excretion →	+1.173	+0.695	<.001	.008	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,652 associations by consensus.

Response to acetaldehyde by HS3ST3B1 expression — BONE

Explore this box plot interactively →