HS2ST1

Across TCGA patient cohorts, HS2ST1 protein abundance is significantly associated with the RNA expression of many other genes, with 6,893 significant associations in total. GBM shows the largest number of these associations.

The most reproducible HS2ST1-associated genes across cancer lineages are CRHBP, CPD, and EVA1A. Each is linked with HS2ST1 in more than 3 cancer types. Because this analysis shows association rather than direction, both HS2ST1-to-partner and partner-to-HS2ST1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, HS2ST1 versus CRHBP in GBM, with a Pearson correlation of -0.38.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (HS2ST1→partner) and Y-score (partner→HS2ST1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	CRHBP →	-0.964	-0.616	<.001	<.001	3	4
LUAD	CPD →	+1.142	+0.488	<.001	.002	3	3
OV	EVA1A →	+0.816	+0.531	.001	<.001	3	3
GBM	PEG3 →	-1.459	-0.498	<.001	<.001	3	3
GBM	SEPTIN4 →	-1.347	-0.621	<.001	<.001	3	3
CCRCC	HRC →	-0.619	-0.334	.002	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,893 associations by consensus.

HS2ST1 vs CRHBP — GBM

Explore this scatter interactively →