Across TCGA cell cohorts, HRNR RNA expression is significantly associated with the go_rna of many other GO terms, with 1,768 significant associations in total. BREAST shows the largest number of these associations.

The most reproducible HRNR-associated GO terms across cancer lineages are Regulation of tumor necrosis factor-mediated signaling pathway, Regulation of plasma membrane repair, and Negative regulation of molecular function. Each is linked with HRNR in more than 7 cancer types. Because this analysis shows association rather than direction, both HRNR-to-partner and partner-to-HRNR results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (HRNR→partner) and Y-score (partner→HRNR) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Lymphoma	Regulation of tumor necrosis factor-mediated signaling pathway →	+0.079	+0.286	<.001	.002	3	7
LUNG_SCLC	Regulation of plasma membrane repair →	+0.280	+0.401	<.001	.001	2	8
BREAST	Negative regulation of molecular function →	+0.083	+0.262	<.001	.001	3	7
UPPER_AERODIGESTIVE_TRACT	Response to UV →	+0.048	+0.283	.004	.008	2	8
BREAST	Regulation of binding →	+0.070	+0.210	<.001	<.001	3	6
BREAST	Nuclear transport →	+0.053	+0.171	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,768 associations by consensus.

Exploration

HRNR survival (RNA) · tumor vs normal (RNA) · all HRNR data types