HRK

Across TCGA patient cohorts, HRK RNA expression is significantly associated with the RNA expression of many other genes, with 15,680 significant associations in total. TGCT shows the largest number of these associations.

The most reproducible HRK-associated genes across cancer lineages are USP49, SPRING1, and LRRC37B. Each is linked with HRK in more than 19 cancer types. Because this analysis shows association rather than direction, both HRK-to-partner and partner-to-HRK results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, HRK versus USP49 in SCLC, with a Pearson correlation of 0.39.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (HRK→partner) and Y-score (partner→HRK) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SCLC	USP49 →	+1.147	+1.021	<.001	<.001	3	18
LIHC	SPRING1 →	+1.145	+0.140	<.001	.004	1	20
TGCT	LRRC37B →	+0.636	+0.940	<.001	<.001	3	17
GBM	CAMSAP1 →	+0.660	+0.836	<.001	<.001	3	17
UCS	NPTXR →	+1.361	+0.800	.002	<.001	3	16
LAML	RNFT2 →	+0.827	+0.132	<.001	.001	3	16

Each partner links to its Q-omics profile. Showing the 6 strongest of 15,680 associations by consensus.

HRK vs USP49 — SCLC

Explore this scatter interactively →